About SynapDx

SynapDx is a laboratory services company developing a blood-based test for the early detection of Autism Spectrum Disorder (ASD). ASD is characterized by impairment in language and socialization as well as restricted and repetitive behaviors. ASD affects 1 in 68 children according to the Centers for Disease Control and Prevention.1

The average age of diagnosis is 4.5 years, yet the average age of first concern is 19 months.1,2 Early diagnosis leads to early treatment – and early treatment is believed to yield better outcomes.3-6 Today, ASD is diagnosed using a variety of assessments that combine direct patient observation and medical history. The addition of a clinically meaningful blood test could hasten the diagnostic process and help children at risk for ASD get access to the right evaluations earlier – and end up with better outcomes as they grow.

SynapDx's approach measures a variety of biomarkers with the goal of developing the most informative test possible. SynapDx has just finished enrolling one of the largest prospective multi-site clinical studies to validate its approach.

 

 

  1. Centers for Disease Control and Prevention (2014). Prevalence of autism spectrum disorder among children aged 8 years — autism and developmental disabilities monitoring network, 11 Sites, United States, 2010. Retrieved from http://www.cdc.gov/mmwr/preview/mmwrhtml/ss6302a1.htm?s_cid=ss6302a1_w
  2. Rebecca E. Rosenberg, Rebecca Landa, J. Kiely Law, Elizabeth A. Stuart, and Paul A. Law, “Factors Affecting Age at Initial Autism Spectrum Disorder Diagnosis in a National Survey,” Autism Research and Treatment, vol. 2011, Article ID 874619, 11 pages, 2011. doi:10.1155/2011/874619
  3. Fein D, Barton M, Eigsti IM, et al. Optimal outcome in individuals with a history of autism. J Child Psychol Psychiatry. 2013;54: 195–205
  4. Orinstein AJ, Helt M, Trob E, Tyson KE, Baton ML, Eigsti IM, Naigles L, Fein D. Intervention for optimal outcome in children and adolescents with a history of autism. J Dev Behav Pedaitr. 2014; 35; 247-256
  5. Lovaas, OI.  Behavioral treatment and normal educational and intellectual functioning in young autistic children.  J Consult Clin Psychol 55:3 (1987).
  6. Dawson G, Rogers S, Munson J, et al. Randomized, controlled trial of an intervention for toddlers with autism: the Early Start Denver Model. Pediatrics. 2010;125:e17–e23